Closantel; a veterinary drug with potential severe morbidity in humans
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Closantel; a veterinary drug with potential severe morbidity in humans
BACKGROUND Closantel is a halogenated salicylanilide with a potent anti parasitic activity. It is widely used in management of parasitic infestation in animals, but is contraindicated in humans. CASE PRESENTATION A 34-year-old man with depression was referred to our center with progressive loss of vision in both eyes 10 days after unintentional ingestion of three 500 mg tablets of Closantel. ...
متن کاملHarmful Use of Veterinary Drugs: Blindness Following Closantel Poisoning in a 5-Year-Old Girl
Background: Closantel is a veterinary drug used as anthelmintic for ruminants while it is contraindicated for humans. This report describes a rare case of blindness, increased liver enzymes and coagulopathy following closantel poisoning. Case report: A 5-year-old girl was presented with acute blindness following closantel poisoning. She was given mistakenly a dose of 500 mg/day (25mg/kg/day) fo...
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A range of topical products are used in veterinary medicine. The efficacy of many of these products has been enhanced by the addition of penetration enhancers. Evolution has led to not only a highly specialized skin in animals and humans, but also one whose anatomical structure and skin permeability differ between the various species. The skin provides an excellent barrier against the ingress o...
متن کاملharmful use of veterinary drugs: blindness following closantel poisoning in a 5-year-old girl
background: closantel is a veterinary drug used as anthelmintic for ruminants while it is contraindicated for humans. this report describes a rare case of blindness, increased liver enzymes and coagulopathy following closantel poisoning. case report: a 5-year-old girl was presented with acute blindness following closantel poisoning. she was given mistakenly a dose of 500 mg/day (25mg/kg/day) fo...
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ژورنال
عنوان ژورنال: BMC Ophthalmology
سال: 2016
ISSN: 1471-2415
DOI: 10.1186/s12886-016-0387-x